Mal-PEG4-VA-PBD
Based on 1 Customer Validation
Mal-PEG4-VA-PBD is a agent-linker conjugate for ADC by using the antitumor antibiotic, Pyrrolobenzodiazepine (PBD), linked via Mal-PEG4-VA.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 88.94%
- CAS 番号: 1342820-68-1
- 分子式: C68H79N9O17
- 分子量:1294.40
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保管条件:
-80°C, stored under nitrogen
生物活性
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Pyrrolobenzodiazepines |
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 1342820-68-1
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性状 Solid
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分子量 1294.40
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分子式 C68H79N9O17
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Color Light yellow to yellow
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SMILES
[H][C@]12N(C(C3=CC(OC)=C(OCCCOC4=C(C=C5C(N=C[C@@]6([H])N(C=C(C7=CC=C(OC)C=C7)C6)C5=O)=C4)OC)C=C3N=C2)=O)C=C(C8=CC=C(NC([C@H](C)NC([C@H](C(C)C)NC(CCOCCOCCOCCOCCNC(CCN9C(C=CC9=O)=O)=O)=O)=O)=O)C=C8)C1
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輸送条件
Shipping with dry ice.
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保管条件
-80°C, stored under nitrogen
溶剤 & 溶解度
DMSO : 100 mg/mL (77.26 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months (stored under nitrogen). When stored at -80°C, please use it within 6 months.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months (stored under nitrogen). When stored at -80°C, please use it within 6 months.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (245 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months (stored under nitrogen). When stored at -80°C, please use it within 6 months.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.7726 mL | 3.8628 mL | 7.7256 mL | 19.3140 mL |
| 5 mM | 0.1545 mL | 0.7726 mL | 1.5451 mL | 3.8628 mL | |
| 10 mM | 0.0773 mL | 0.3863 mL | 0.7726 mL | 1.9314 mL | |
| 15 mM | 0.0515 mL | 0.2575 mL | 0.5150 mL | 1.2876 mL | |
| 20 mM | 0.0386 mL | 0.1931 mL | 0.3863 mL | 0.9657 mL | |
| 25 mM | 0.0309 mL | 0.1545 mL | 0.3090 mL | 0.7726 mL | |
| 30 mM | 0.0258 mL | 0.1288 mL | 0.2575 mL | 0.6438 mL | |
| 40 mM | 0.0193 mL | 0.0966 mL | 0.1931 mL | 0.4828 mL | |
| 50 mM | 0.0155 mL | 0.0773 mL | 0.1545 mL | 0.3863 mL | |
| 60 mM | 0.0129 mL | 0.0644 mL | 0.1288 mL | 0.3219 mL |