MDL-27531
MDL-27531 acts functionally like a glycine agonist. MDL-27531 selectively reduces hindlimb contractions. MDL-27531 selectively reverses strychnine-induced seizures in mice. MDL-27531 inhibits pentylenetetrazol-induced seizures with an ED50 of 55 mg/kg. MDL-27531 promotes the binding of benzodiazepine antagonist Ro 15-1788 to cerebral cortex of mice without changing GABA levels. MDL-27531 can be studied in research on reflex control dysfunction.
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- CAS 番号: 116850-44-3
- 分子式: C10H11N3O2S
- 分子量:237.28
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
製品説明
化学情報
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CAS 番号 116850-44-3
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分子量 237.28
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分子式 C10H11N3O2S
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SMILES
O=S(=O)(C1=NN=C(C=2C=CC=CC2)N1C)C
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Kehne, J. H., et al., (1992). MDL 27,531 reduces spontaneous hindlimb contractions in rats with chronic transections of the spinal cord. Neuroscience letters, 147(1), 101–105. [Content Brief]
[2]. Kehne, J. H., et al., (1992). MDL 27,531 selectively reverses strychnine-induced seizures in mice. British journal of pharmacology, 106(4), 910–916. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
MDL-27531 関連分類
HY-W975902 関連分類
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