PROTAC BRD9-binding moiety 5
PROTAC BRD9-binding moiety 5 is a selective BRD9 binder with an IC50 value of 4.20 μM, can be used for the synthesis of PROTACs. PROTAC BRD9-binding moiety 5 has antiproliferative activity against cancer cells.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 893633-37-9
- 分子式: C19H18N6O
- 分子量:346.39
-
保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
生物活性
-
化学情報
- 純度とドキュメンテーション
- 参考文献
-
Help & FAQs
生物活性
|
BRD9 4.2 μM (IC50) |
PROTAC BRD9-binding moiety 5 (compound 7) (0-250 μM; 48h) has antiproliferative activity against Jurkat, MDA-MB-231, A375 and HCT-116[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
-
Cell Line:Jurkat, MDA-MB-231, A375 and HCT-116
-
Concentration:0-250 μM
-
Incubation Time:48h
-
Result:Exhibited antiproliferative activity against Jurkat, MDA-MB-231, A375 and HCT-116 with IC50s of 77 ± 7 μM, 125 ± 8 μM, 133 ± 5 μM and 145 ± 3 μM.
化学情報
-
CAS 番号 893633-37-9
-
分子量 346.39
-
分子式 C19H18N6O
-
SMILES
CCC1=NN=C2C(NC3=CC(NC(C)=O)=CC=C3)=NC4=C(N12)C=CC=C4
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
PROTAC BRD9-binding moiety 5 関連分類
HY-143270 関連分類
Powered by Bioz