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Cat. No.: HY-107626A

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ATC0065 free base

ATC0065 free base is a potent, selective and orally active melanin-concentrating hormone (MCH) receptor 1 (MCHR1) antagonist with an IC₅₀ of 15.7 nM for human MCHR1. ATC0065 free base does not exhibits significant activity for MCHR2. ATC0065 free base has anxiolytic and antidepressant activities.

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CAS No.: 509145-82-8
화학식: C₂₅H₂₉BrF₃N₅O
분자량:552.43

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

ATC0065 free base Chemical Structure

CAS No.: 509145-82-8

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

All 5-HT Receptor Isoforms :

Chemical Information

CAS No. 509145-82-8
분자량 552.43
화학식 C₂₅H₂₉BrF₃N₅O
SMILES

CN(C1=NC(N[C@H]2CC[C@H](CC2)NCCC3=C(C=C(C=C3)Br)OC(F)(F)F)=NC4=C1C=CC=C4)C
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Shigeyuki Chaki, et al. Anxiolytic- and antidepressant-like profile of ATC0065 and ATC0175: nonpeptidic and orally active melanin-concentrating hormone receptor 1 antagonists. J Pharmacol Exp Ther. 2005 May;313(2):831-9. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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Biological Activity
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Chemical Information
순도&문서
References

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ATC0065 free base

All 5-HT Receptor Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

ATC0065 free base Related Classifications

HY-107626A Related Classifications