Limd1 - LIM domains containing 1 Gene
Also Known as D9Ertd192e
Species: Mus musculus
Summary
Enables transcription corepressor activity. Involved in negative regulation of canonical Wnt signaling pathway; negative regulation of osteoblast differentiation; and osteoblast development. Located in cytoplasm. Is expressed in several structures, including branchial arch; early conceptus; genitourinary system; hemolymphoid system; and limb. Orthologous to human LIMD1 (LIM domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]
Limd1 Products (2)
| mRNA | Protein | Name |
|---|---|---|
| NM_001410486.1 | NP_001397415.1 | LIM domain-containing protein 1 isoform 2 |
| NM_013860.3 | NP_038888.2 | LIM domain-containing protein 1 isoform 1 |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
17092936 | MGI |
| enables transcription corepressor activity |
IDA
IDA: Inferred from direct assay
|
17909014 | MGI |
| Biological Process GO Annotation | Evidence | References | Source |
|---|---|---|---|
| involved in negative regulation of canonical Wnt signaling pathway |
IMP
IMP: Inferred from mutant phenotype
|
18657804 | MGI |
| involved in negative regulation of osteoblast differentiation |
IMP
IMP: Inferred from mutant phenotype
|
18657804 | MGI |
| involved in osteoblast development |
IMP
IMP: Inferred from mutant phenotype
|
17092936 | MGI |
| Cellular Component GO Annotation | Evidence | References | Source |
|---|---|---|---|
| located in cytoplasm |
IDA
IDA: Inferred from direct assay
|
18657804 | MGI |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
LIM domain-containing protein 1 |
|