L-Glutamic acid-13C5
Based on 1 publication(s) in Google Scholar
L-Glutamic acid-13C5 is the 13C-labeled L-Glutamic acid. L-Glutamic acid acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA). L-Glutamic acid shows a direct activating effect on the release of DA from dopaminergic terminals.
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- Purity: 99.81%
- CAS No.: 55443-55-5
- 화학식: 13C5H9NO4
- 분자량:152.09
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보관:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Publications Citing Use of MedChemExpress (MCE) L-Glutamic acid-13C5
MoreAll Endogenous Metabolite Isoforms
MoreAll iGluR Isoforms
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Biological Activity
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NMDA Receptor |
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 55443-55-5
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Unlabeled Cas 56-86-0
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Appearance Solid
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분자량 152.09
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화학식 13C5H9NO4
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Color White to off-white
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SMILES
O[13C]([13CH2][13CH2][13C@H](N)[13C](O)=O)=O
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
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Journal Impact Factor
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Most Recent
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Neuron
Comprehensive characterization of metabolic consumption and production by the human brain. [Abstract]2025 Jun 4;113(11):1708-1722.e5. PMID: 40147438
용액&용해도
H2O : 5 mg/mL (32.88 mM; ultrasonic and warming and heat to 60°C)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (274 KB)
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SDS (396 KB)
- English - EN (396 KB)
- Français - FR (396 KB)
- Deutsch - DE (396 KB)
- Norwegian - NO (396 KB)
- Español - ES (396 KB)
- Swedish - SV (396 KB)
- Italian - IT (396 KB)
- Korean - KR (396 KB)
- Portuguese - PT (396 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 6.5751 mL | 32.8753 mL | 65.7505 mL | 164.3764 mL |
| 5 mM | 1.3150 mL | 6.5751 mL | 13.1501 mL | 32.8753 mL | |
| 10 mM | 0.6575 mL | 3.2875 mL | 6.5751 mL | 16.4376 mL | |
| 15 mM | 0.4383 mL | 2.1917 mL | 4.3834 mL | 10.9584 mL | |
| 20 mM | 0.3288 mL | 1.6438 mL | 3.2875 mL | 8.2188 mL | |
| 25 mM | 0.2630 mL | 1.3150 mL | 2.6300 mL | 6.5751 mL | |
| 30 mM | 0.2192 mL | 1.0958 mL | 2.1917 mL | 5.4792 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.