2. Academic Validation
  3. Discovery of a new and efficient small molecule for neuronal differentiation from mesenchymal stem cell

Discovery of a new and efficient small molecule for neuronal differentiation from mesenchymal stem cell

  • J Med Chem. 2009 Dec 24;52(24):7931-3. doi: 10.1021/jm9015558.
Na Ri Kim 1,  Seung Kyu Kang,  Hyun Hee Ahn,  Sung Wook Kwon,  Woul Seong Park,  Ki Suk Kim,  Sung Soo Kim,  Hee Jung Jung,  Sang Un Choi,  Jin Hee Ahn,  Kwang Rok Kim
Affiliations

Affiliation

  • 1 Korea Research Institute of Chemical Technology, Daejeon, 305-600, Korea.
PMID: 20014867 DOI: 10.1021/jm9015558
Abstract

A new synthetic small molecule, compound 1, which induced a neuronal differentiation from mesenchymal stem cells (MSCs) with an excellent efficiency, was identified. Furthermore the differentiated cell by 1 showed the neural electrophysiological and cholinergic neuron properties.

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