N-Nitroso-3-azabicyclo[3.3.0]octane-d₄

Cat. No.: HY-143812S Pureza: 95.0%: Ficha de datos
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N-Nitroso-3-azabicyclo[3.3.0]octane-d₄ is the deuterium labeled N-Nitroso-3-azabicyclo[3.3.0]octane.

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N-Nitroso-3-azabicyclo[3.3.0]octane-d<sub>4</sub>

N-Nitroso-3-azabicyclo[3.3.0]octane-d₄ Estructura química

No. CAS : 1346604-35-0

Tamaño	Stock	Cantidad
Liquid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	Obtener un presupuesto 2-4 weeks 2-4 weeks 2-4 weeks 2-4 weeks	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	Obtener un presupuesto 2-4 weeks 2-4 weeks 2-4 weeks 2-4 weeks	Estimated Time of Arrival: December 31
Liquid
5 mg	En stock	Estimated Time of Arrival: December 31
10 mg	En stock	Estimated Time of Arrival: December 31
25 mg	En stock	Estimated Time of Arrival: December 31
50 mg	En stock	Estimated Time of Arrival: December 31
100 mg	En stock	Estimated Time of Arrival: December 31
200 mg	Obtener un presupuesto
500 mg	Obtener un presupuesto

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Descripciòn

N-Nitroso-3-azabicyclo[3.3.0]octane-d₄ is the deuterium labeled N-Nitroso-3-azabicyclo[3.3.0]octane^[1].

Application

1. This compound can be used as a tracer.
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Peso molecular

144.21

Fòrmula

C₇H₈D₄N₂O

No. CAS

1346604-35-0

Unlabeled CAS

54786-86-6

Appearance

Liquid

Color

Light yellow to yellow

SMILES

O=NN1C([2H])([2H])C2C(CCC2)C1([2H])[2H]

Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

Pure form	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvente y solubilidad

In Vitro:

DMSO : 100 mg/mL (693.43 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	6.9343 mL	34.6717 mL	69.3433 mL
5 mM	1.3869 mL	6.9343 mL	13.8687 mL
10 mM	0.6934 mL	3.4672 mL	6.9343 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Calculadora de molaridad
Calculadora de dilución

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Pureza y Documentación

Purity: 95.0%

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Ficha de datos (274 KB) SDS (252 KB)

COA (255 KB) HNMR (235 KB) MS (71 KB)

Instrucciones de manejo (2659 KB)

Referencias

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	6.9343 mL	34.6717 mL	69.3433 mL	173.3583 mL
	5 mM	1.3869 mL	6.9343 mL	13.8687 mL	34.6717 mL
	10 mM	0.6934 mL	3.4672 mL	6.9343 mL	17.3358 mL
	15 mM	0.4623 mL	2.3114 mL	4.6229 mL	11.5572 mL
	20 mM	0.3467 mL	1.7336 mL	3.4672 mL	8.6679 mL
	25 mM	0.2774 mL	1.3869 mL	2.7737 mL	6.9343 mL
	30 mM	0.2311 mL	1.1557 mL	2.3114 mL	5.7786 mL
	40 mM	0.1734 mL	0.8668 mL	1.7336 mL	4.3340 mL
	50 mM	0.1387 mL	0.6934 mL	1.3869 mL	3.4672 mL
	60 mM	0.1156 mL	0.5779 mL	1.1557 mL	2.8893 mL
	80 mM	0.0867 mL	0.4334 mL	0.8668 mL	2.1670 mL
	100 mM	0.0693 mL	0.3467 mL	0.6934 mL	1.7336 mL