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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
99 Results for "
parathyroid-hormone
" in MedChemExpress (MCE) Product Catalog:
Products (99)
99 Results for "parathyroid-hormone" in MCE Product Catalog:
15
15 Publications Verification
Cat. No.: HY-50919
CAS No.: 131918-61-1
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Paricalcitol, a vitamin D analogue, is a vitamin D receptor agonist, used for the prevention and treatment of secondary hyperparathyroidism (excessive secretion of parathyroid hormone) associated with chronic renal failure.
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11 Cited Publications
Cat. No.: HY-P0059
CAS No.: 52232-67-4
Synonyms: Human parathyroid hormone-(1-34); hPTH (1-34)
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4
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Seeds of Cassia tora Linn. Quinones other families Leguminosae Anthraquinones Phenols Polyphenols Plants Disease Research Fields Cancer
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3
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Evocalcet (KHK7580) is an orally active calcium sensing receptor (CaSR) agonist. Evocalcet inhibits the secretion of parathyroid hormone (PTH) from parathyroid gland cells. Evocalcet can be used for the research of hyperparathyroidism .
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3 Cited Publications
Synonyms: BA 058; BIM 44058
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3
3 Cited Publications
Cat. No.: HY-P1252
CAS No.: 12583-68-5
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3
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2
2 Cited Publications
Cat. No.: HY-P1955A
CAS No.: 1334237-71-6
Synonyms: Velcalcetide hydrochloride; AMG 416 hydrochloride; KAI-4169 hydrochloride
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2
2 Cited Publications
Cat. No.: HY-P2279
CAS No.: 98614-76-7
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2
2 Cited Publications
Cat. No.: HY-P2279A
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PCO371 is an orally active full agonist of parathyroid hormone receptor 1 (PTHR1), with no effect on PTH type 2 receptor.
Synonyms: CLTX-305; JTT-305; MK-5442
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Encaleret (CLTX-305) is an orally active antagonist of the calcium-sensing receptor (CaSR), with an IC50 of 12 nM. Encaleret exerts its effect by inhibiting the excessive activity of functional gain-of-function CaSR variants, and can restore blood calcium levels, promote the secretion of parathyroid hormone, improve magnesium and phosphorus metabolism, and increase urinary calcium excretion. Encaleret can be used in the research of diseases such as osteoporosis and autosomal dominant hypocalcemia type 1 .
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Dihydrotachysterol is a synthetic analog of vitamin D. Dihydrotachysterol can be used to for the research of hypocalcemia (lack of calcium in the blood) and hypoparathyroidism (lack of parathyroid hormone in the body) .
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AH3960 (compound 16c) is an antagonist of androgen receptor. AH3960 binds wild as well as T877 mutant type androgen receptors. AH3960 selectively inhibits T877 with an IC50 value of 0.82 μM. AH3960 also serves as an agonist of parathyroid hormone receptor-1 (PTHR1) .
Cat. No.: HY-P2426
CAS No.: 118102-98-0
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DS69910557 is a potent, selective and orally activehuman parathyroid hormone receptor 1 (hPTHR1) antagonist. DS69910557 has antagonistic activity for PTHR1 with an IC50 value of 0.08 μM. DS69910557 can be used for the research of hyperparathyroidism, hypercalcemia of malignancy and osteoporosis .
Cat. No.: HY-P10909
CAS No.: 2925554-87-4
Synonyms: MBX 2109
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Synonyms: SK-1403; AJT240; PLS240
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Upacicalcet sodium is a non-peptide calcimimetic that acts as a CaSR agonist (EC50 = 10.8 nM). Upacicalcet sodium reduces serum intact parathyroid hormone (iPTH) and serum Ca 2+ levels, reducing hypocalcemia and gastrointestinal complications. Upacicalcet sodium sodium improves vascular calcification and bone disorders in the Adenine (HY-B0152)-induced secondary hyperparathyroidism (SHPT) rat model. Upacicalcet sodium sodium inhibits cortical pore formation and reduces bone fibrosis in rats with chronic kidney disease (CKD). Upacicalcet sodium is useful for studying SHPT .
Cat. No.: HY-W145486
CAS No.: 299-28-5
Cat. No.: HY-76585
CAS No.: 2070009-67-3
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
