1. GPCR/G Protein
  2. CaSR
  3. Etelcalcetide hydrochloride

Etelcalcetide hydrochloride (Synonyms: AMG 416 hydrochloride; KAI-4169 hydrochloride)

Cat. No.: HY-P1955A Purity: 99.61%
Handling Instructions

Etelcalcetide hydrochloride (AMG 416 hydrochloride) is a synthetic peptide as an activator of the calcium sensing receptor (CaSR). Etelcalcetide hydrochloride is effective in lowering parathyroid hormone (PTH) concentrations in patients receiving dialysis with secondary hyperparathyroidism receiving hemodialysis.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Etelcalcetide hydrochloride Chemical Structure

Etelcalcetide hydrochloride Chemical Structure

CAS No. : 1334237-71-6

Size Price Stock Quantity
1 mg USD 44 In-stock
Estimated Time of Arrival: December 31
5 mg USD 110 In-stock
Estimated Time of Arrival: December 31
10 mg USD 208 In-stock
Estimated Time of Arrival: December 31
25 mg USD 416 In-stock
Estimated Time of Arrival: December 31
50 mg   Get quote  
100 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

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Description

Etelcalcetide hydrochloride (AMG 416 hydrochloride) is a synthetic peptide as an activator of the calcium sensing receptor (CaSR). Etelcalcetide hydrochloride is effective in lowering parathyroid hormone (PTH) concentrations in patients receiving dialysis with secondary hyperparathyroidism receiving hemodialysis[1].

Clinical Trial
Molecular Weight

1353.33

Formula

C38H73N21O10S2.17/2HCl

CAS No.
Sequence Shortening

C1' . Ac-{d-Cys1}-{d-Ala}-{d-Arg}-{d-Arg}-{d-Arg}-{d-Ala}-{d-Arg}-NH2 (Disulfide bridge: Cys1'-Cys1)

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (73.89 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.7389 mL 3.6946 mL 7.3892 mL
5 mM 0.1478 mL 0.7389 mL 1.4778 mL
10 mM 0.0739 mL 0.3695 mL 0.7389 mL
*Please refer to the solubility information to select the appropriate solvent.
Purity & Documentation

Purity: 99.61%

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This equation is commonly abbreviated as: C1V1 = C2V2

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Product Name:
Etelcalcetide hydrochloride
Cat. No.:
HY-P1955A
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