1. GPCR/G Protein
  2. CaSR
  3. Etelcalcetide

Etelcalcetide (Synonyms: AMG 416; KAI-4169)

Cat. No.: HY-P1955
Handling Instructions

Etelcalcetide (AMG 416) is a synthetic peptide as an activator of the calcium sensing receptor (CaSR). Etelcalcetide is effective in lowering parathyroid hormone (PTH) concentrations in patients receiving dialysis with secondary hyperparathyroidism receiving hemodialysis.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Etelcalcetide Chemical Structure

Etelcalcetide Chemical Structure

CAS No. : 1262780-97-1

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Description

Etelcalcetide (AMG 416) is a synthetic peptide as an activator of the calcium sensing receptor (CaSR). Etelcalcetide is effective in lowering parathyroid hormone (PTH) concentrations in patients receiving dialysis with secondary hyperparathyroidism receiving hemodialysis[1].

Molecular Weight

1048.25

Formula

C₃₈H₇₃N₂₁O₁₀S₂

CAS No.

1262780-97-1

Sequence

{Cys1'}-Ac-{d-Cys1}-{d-Ala}-{d-Arg}-{d-Arg}-{d-Arg}-{d-Ala}-{d-Arg}-NH2 (Disulfide bridge: Cys1'-Cys1)

Sequence Shortening

C'-Ac-d-C-d-A-d-R-d-R-d-R-d-A-d-R-NH2 (Disulfide bridge: Cys1'-Cys1)

Shipping

Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Etelcalcetide
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HY-P1955
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