118102-98-0
Chemical Structure
(D-Trp12,Tyr34)-pTH (7-34) amide (bovine)
- CAS No.: 118102-98-0
- Formula:C165H251N49O40S2
- Molecular Weight:3625.25
InChIKey: VNWKTOKETHGBQD-UHFFFAOYSA-N
SMILES: [FMHNL-{d-Trp}-KHLSSMERVEWLRKKLQDVHNY-NH2]
Biological Activity: (D-Trp12,Tyr34)-pTH (7-34) amide (bovine) is a potent and competitive antagonist of parathyroid hormone (PTH), with a Ki of 69 nM in bovine renal cortical membrane. (D-Trp12,Tyr34)-pTH (7-34) amide (bovine) can be used for growth and development regulation[1][2].
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(D-Trp12,Tyr34)-pTH (7-34) amide (bovine) | 99.70% | (D-Trp12,Tyr34)-pTH (7-34) amide (bovine) is a potent and competitive antagonist of parathyroid hormone (PTH), with a Ki of 69 nM in bovine renal cortical membrane. (D-Trp12,Tyr34)-pTH (7-34) amide (bovine) can be used for growth and development regulation. | ||||||||||||||||||||
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- [1]. Goldma ME, et, al. A new highly potent parathyroid hormone antagonist: [D-Trp12,Tyr34]bPTH-(7-34)NH2. Endocrinology. 1988 Nov; 123(5): 2597-9. [Content Brief]
- [2]. Pizurki L, et, al. Inhibition by (D-Trp12,Tyr34)bPTH(7-34)amide of PTH and PTHrP effects on Pi transport in renal cells. Am J Physiol. 1990 Aug; 259(2 Pt 2): F389-92. [Content Brief]