67-96-9
67-96-9
Chemical Structure
Dihydrotachysterol
- CAS No.: 67-96-9
- Formula:C28H46O
- Molecular Weight:398.66
IUPAC Name: (1S,4S,E)-3-(2-((1R,3aS,7aR,E)-1-((2R,5R,E)-5,6-dimethylhept-3-en-2-yl)-7a-methyloctahydro-4H-inden-4-ylidene)ethylidene)-4-methylcyclohexan-1-ol
InChIKey: ILYCWAKSDCYMBB-OPCMSESCSA-N
SMILES: C[C@@]12[C@](CC[C@]2([H])[C@H](C)/C=C/[C@H](C)C(C)C)([H])/C(CCC1)=C/C=C3[C@H](CC[C@@H](C/3)O)C
Biological Activity: Dihydrotachysterol is a synthetic analog of vitamin D. Dihydrotachysterol can be used to for the research of hypocalcemia (lack of calcium in the blood) and hypoparathyroidism (lack of parathyroid hormone in the body) [1][2].
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Dihydrotachysterol | 98.94% | Dihydrotachysterol is a synthetic analog of vitamin D. Dihydrotachysterol can be used to for the research of hypocalcemia (lack of calcium in the blood) and hypoparathyroidism (lack of parathyroid hormone in the body) . | ||||||||||||||||||||
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Dihydrotachysterol (Standard) | ≥98% | Dihydrotachysterol (Standard) is the analytical standard of Dihydrotachysterol (HY-A0245). This product is intended for research and analytical applications. Dihydrotachysterol is a synthetic analog of vitamin D. Dihydrotachysterol can be used to for the research of hypocalcemia (lack of calcium in the blood) and hypoparathyroidism (lack of parathyroid hormone in the body) . | ||||||||||||||||||||
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Ercalcidiol-13C5 | 25-Hydroxyvitamin D2-(20,21,22,26,27-13C5) solution is the 13C labeled 25-Hydroxyvitamin D2. | |||||||||||||||||||||
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Doxercalciferol | 99.85% | Doxercalciferol is a Vitamin D2 analog, acts as an activator of Vitamin D receptor, and prevent renal disease. | ||||||||||||||||||||
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Ercalcidiol | 99.75% | Ercalcidiol is a metabolite of vitamin D2, is regarded as an indicator of vitamin D nutritional status. | ||||||||||||||||||||
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Ercalcidiol-13C3 | Ercalcidiol-13C3 (25-Hydroxy Vitamin D2-13C3) is the 13C-labeled Ercalcidiol (HY-32349). Ercalcidiol is a metabolite of vitamin D2, is regarded as an indicator of vitamin D nutritional status. | |||||||||||||||||||||
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Paricalcitol (Standard) | ≥98% | Paricalcitol (Standard) is the analytical standard of Paricalcitol. This product is intended for research and analytical applications. Paricalcitol, a vitamin D analogue, is a vitamin D receptor agonist, used for the prevention and treatment of secondary hyperparathyroidism (excessive secretion of parathyroid hormone) associated with chronic renal failure. | ||||||||||||||||||||
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trans-Doxercalciferol | 98.20% | trans-Doxercalciferol is an isomer of Doxercalciferol (HY-32348). Doxercalciferol is a vitamin D receptor agonist. Doxercalciferol reduces proteinuria, podocyte injury, mesangial expansion, extracellular matrix accumulation, macrophage infiltration, oxidative stress, proinflammatory cytokines, profibrotic growth factors, renal neutral lipid accumulation, albuminuria and glomerulosclerosis. Doxercalciferol alleviates high-salt diet-induced myocardial hypertrophy. trans-Doxercalciferol is used for the research of diet-induced obesity-related nephropathy, diabetic nephropathy, myocardial hypertrophy, cardiac dysfunction and secondary hyperparathyroidism. | ||||||||||||||||||||
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Vitamin D2 | 99.11% | Vitamin D2 (Ergocalciferol), drived from plant sources or dietary supplements, could be used as supplement of Vitamin D. |
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5,6-trans-Vitamin D2 | 97.0% | 5,6-trans-Vitamin D2 is the isomer of Vitamin D2. | ||||||||||||||||||||
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(R)-Vitamin D2 | 98.67% | (R)-Vitamin D2 is the isomer of Vitamin D2 (HY-76542), and can be used as an experimental control. Vitamin D2 (Ergocalciferol), drived from plant sources or dietary supplements, could be used as supplement of Vitamin D. |
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Impurity of Doxercalciferol | Impurity of Doxercalciferol is an impurity of doxercalciferol, which is a synthetic analog of ergocalciferol (vitamin D2), used as a agent for secondary hyperparathyroidism and metabolic bone disease, and it suppresses parathyroid synthesis and secretion. | |||||||||||||||||||||
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References
- [1]. I Quack, et al. Dihydrotachysterol therapy for hypoparathyroidism: consequences of inadequate monitoring. Five cases and a review. Exp Clin Endocrinol Diabetes. 2005 Jul;113(7):376-80. [Content Brief]
- [2]. M E Peterson, et al. Idiopathic hypoparathyroidism in five cats. J Vet Intern Med. Jan-Feb 1991;5(1):47-51. [Content Brief]
