1. Vitamin D Related
  2. VD/VDR
  3. Dihydrotachysterol

Dihydrotachysterol 

Cat. No.: HY-A0245
Handling Instructions

Dihydrotachysterol is a synthetic analog of vitamin D. Dihydrotachysterol can be used to for the research of hypocalcemia (lack of calcium in the blood) and hypoparathyroidism (lack of parathyroid hormone in the body) .

For research use only. We do not sell to patients.

Dihydrotachysterol Chemical Structure

Dihydrotachysterol Chemical Structure

CAS No. : 67-96-9

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Description

Dihydrotachysterol is a synthetic analog of vitamin D. Dihydrotachysterol can be used to for the research of hypocalcemia (lack of calcium in the blood) and hypoparathyroidism (lack of parathyroid hormone in the body) [1][2].

In Vitro

Dihydrotachysterol is effective in the elevation of serum calcium by stimulating intestinal calcium absorption and mobilizing bone calcium in the absence of parathyroid hormone and of functioning renal tissue[1].
Dihydrotachysterol also increases renal phosphate excretion[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Dihydrotachysterol is a potent synthetic vitamin D analogue that is widely available but more expensive than vitamin D2. It has an onset of action and half-life between those of vitamin D2 and calcitriol. Dihydrotachysterol (initially given at 0.03 to 0.08 mg/kg/day for 2 to 3 days. The final dosages range from 0.004 to 0.04 mg/kg/day) is useful for the treatment of hypoparathyroidism[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Animal Model: Five young to middle-aged cats of mixed breeding[2]
Dosage: Initially given at a dosage ranging from 0.03 to 0.08 mg/kg/day for 2 to 3 days. The final dosage ranged from 0.004 to 0.04 mg/kg/day.
Administration: Oral administration
Result: Was useful for the treatment of hypoparathyroidism.
Molecular Weight

398.66

Formula

C28H46O

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Dihydrotachysterol
Cat. No.:
HY-A0245
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