477-85-0
477-85-0
Chemical Structure
Obtusifolin
- CAS No.: 477-85-0
- Formula:C16H12O5
- Molecular Weight:284.26
IUPAC Name: 2,8-dihydroxy-1-methoxy-3-methylanthracene-9,10-dione
InChIKey: NYRXUBDGDSRBGB-UHFFFAOYSA-N
SMILES: O=C1C2=C(C=CC=C2O)C(C3=CC(C)=C(O)C(OC)=C13)=O
Biological Activity: Obtusifolin, isolated from the seeds of Cassia obtusifolia, regulates the gene expression and production of MUC5AC mucin in airway epithelial cells via inhibiting NF-kB pathway[1]. Obtusifolin suppresses phthalate esters-induced breast cancer bone metastasis by targeting parathyroid hormone-related protein[2].
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Obtusifolin | 99.91% | Obtusifolin, isolated from the seeds of Cassia obtusifolia, regulates the gene expression and production of MUC5AC mucin in airway epithelial cells via inhibiting NF-kB pathway. Obtusifolin suppresses phthalate esters-induced breast cancer bone metastasis by targeting parathyroid hormone-related protein. | ||||||||||||||||||||
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Obtusifolin (Standard) | ≥98% | Obtusifolin (Standard) is the analytical standard of Obtusifolin. This product is intended for research and analytical applications. Obtusifolin, isolated from the seeds of Cassia obtusifolia, regulates the gene expression and production of MUC5AC mucin in airway epithelial cells via inhibiting NF-kB pathway. Obtusifolin suppresses phthalate esters-induced breast cancer bone metastasis by targeting parathyroid hormone-related protein. | ||||||||||||||||||||
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References
- [1]. Choi BS, et al. Obtusifolin isolated from the seeds of Cassia obtusifolia regulates the gene expression and production of MUC5AC mucin in airway epithelial cells via affecting NF-κB pathway. Phytother Res. 2019 Apr;33(4):919-928. [Content Brief]
- [2]. Hsu YL, et al. Obtusifolin suppresses phthalate esters-induced breast cancer bone metastasis by targeting parathyroid hormone-related protein. J Agric Food Chem. 2014 Dec 10;62(49):11933-40. [Content Brief]
Keywords
