Toxicity and antiviral activity of cinnabarin obtained from Pycnoporus sanguineus (Fr.) Murr

  • Phytother Res. 2003 Nov;17(9):1069-72. doi: 10.1002/ptr.1304.
A Smânia Jr  1 ,  C J S Marques ,  E F A Smânia ,  C R Zanetti ,  S G Carobrez ,  R Tramonte ,  C Loguercio-Leite
Affiliations
  • 1. Departamento de Microbiologia e Parasitologia, Universidade Federal de Santa Catarina, Florianópolis, Brazil. [email protected]
PMID: 14595589 DOI: 10.1002/ptr.1304
Abstract

This work describes the cytopathic effect on cells, cytotoxic action on mice, and Antiviral activity of cinnabarin. This substance had no effect on mouse neuroblastoma cells (NA cell, ATCC clone C-1300) at a concentration of 0.31 mg/ml, it was not able to cause toxic effects in mice at concentrations of 1000 mg/kg, and reduced by four times the titers of the rabies virus at concentrations of 0.31 mg/ml.

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