Scintillation proximity assay

  • Curr Protoc Neurosci. 2005 Feb:Chapter 7:Unit 7.15. doi: 10.1002/0471142301.ns0715s30.
Steven D Kahl  1 ,  Christian C Felder
Affiliations
  • 1. Lilly Research Laboratories, Indianapolis, Indiana, USA.
PMID: 18428624 DOI: 10.1002/0471142301.ns0715s30
Abstract

Scintillation proximity assay technologies provide a rapid non-separation method to measure common biological interactions using radioactively tagged molecules. This unit identifies potential uses of the technology for the measurement of receptor-ligand binding, cAMP accumulation, GTP binding to heterotrimeric G proteins, Protease activity and cellular uptake.