Elevated NDRG1 Expression Drives Oxaliplatin Chemoresistance in Bladder Cancer Cells by Promoting Homologous Recombination Repair and Inhibiting G2/M Arrest

  • Cell Biochem Biophys. 2025 Dec 10. doi: 10.1007/s12013-025-01961-6.
Yishuang Yan  1 ,  Huayu Zhang  2 ,  Chunshu Jia  3 ,  Hao Xu  1 ,  Si-Si Wang  4 ,  Lei Liu  5
Affiliations
  • 1. Laboratory of Tumor Immunology, The First Hospital of Jilin University, Changchun, 130021, China.
  • 2. School of Pharmaceutical Sciences, Jilin University, Changchun, 130021, China.
  • 3. Prenatal Diagnosis Center, Reproductive Medicine Center, The First Hospital of Jilin University, Changchun, 130021, China.
  • 4. Laboratory of Tumor Immunology, The First Hospital of Jilin University, Changchun, 130021, China. [email protected].
  • 5. Department of ultrasound, The First Hospital of Jilin University, Changchun, 130021, China. [email protected].
PMID: 41369707 DOI: 10.1007/s12013-025-01961-6
Keywords
Bladder cancer; Cell cycle; Chemoresistance; Homologous recombination repair; NDRG1; Oxaliplatin.
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