(R)-AMPA
(R)-AMPA is an inactive AMPA receptor ligand that inhibits the release of excitatory amino acids from neurons. (R)-AMPA is inactive in experiments that enhance the release of [3H]D-aspartate induced by electrical stimulation. (R)-AMPA is inhibited by competitive and noncompetitive AMPA receptor selective antagonists in response to AMPA and glutamate.
For research use only. We do not sell to patients.
- CAS No.: 83654-13-1
- Formula: C7H10N2O4
- Molecular Weight:186.17
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All iGluR Isoforms
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Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| CHO | EC50 |
>1000 μM
Compound: (R)-7
|
Agonist activity of the compound at Metabotropic Excitatory Amino acid Receptors Expressed in CHO cells. mGlu2
Agonist activity of the compound at Metabotropic Excitatory Amino acid Receptors Expressed in CHO cells. mGlu2
|
[PMID: 8759641] |
| CHO | EC50 |
>1000 μM
Compound: (R)-7
|
Agonist activity of the compound at Metabotropic Excitatory Amino acid Receptors Expressed in CHO cells. mGlu6
Agonist activity of the compound at Metabotropic Excitatory Amino acid Receptors Expressed in CHO cells. mGlu6
|
[PMID: 8759641] |
| CHO | EC50 |
>1000 μM
Compound: (R)-7
|
Agonist activity of the compound at Metabotropic Excitatory Amino acid Receptors Expressed in CHO cells. mGlu1-alpha
Agonist activity of the compound at Metabotropic Excitatory Amino acid Receptors Expressed in CHO cells. mGlu1-alpha
|
[PMID: 8759641] |
Chemical Information
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CAS No. 83654-13-1
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Molecular Weight 186.17
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Formula C7H10N2O4
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SMILES
O=C1C(C[C@@H](N)C(O)=O)=C(C)ON1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)