1. Membrane Transporter/Ion Channel
    Neuronal Signaling
    GPCR/G Protein
  2. iGluR
    mGluR
  3. Quisqualic acid

Quisqualic acid (Synonyms: L-Quisqualic acid)

Cat. No.: HY-12597
Handling Instructions

Quisqualic acid (L-Quisqualic acid), a natural analog of glutamate, is a potent and pan two subsets (iGluR and mGluR) of excitatory amino acid (EAA) agonist with an EC50 of 45 nM and a Ki of 10 nM for mGluR1R. Quisqualic acid is isolated from the fruits of Quisqualis chinensis.

For research use only. We do not sell to patients.

Quisqualic acid Chemical Structure

Quisqualic acid Chemical Structure

CAS No. : 52809-07-1

Size Stock
100 mg   Get quote  
250 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Quisqualic acid (L-Quisqualic acid), a natural analog of glutamate, is a potent and pan two subsets (iGluR and mGluR) of excitatory amino acid (EAA) agonist with an EC50 of 45 nM and a Ki of 10 nM for mGluR1R. Quisqualic acid is isolated from the fruits of Quisqualis chinensis[1][2].

IC50 & Target[1]

mGluR1R

45 nM (EC50)

mGluR1R

10 nM (Ki)

mGluR2R

108 μM (IC50)

mGluR2R

113 μM (Ki)

mGluR4R

593 μM (IC50)

mGluR4R

112 μM (Ki)

In Vitro

Quisqualic acid is an agonist of AMPA and metabotropic glutamate receptors. Quisqualic acid activates mGluR2R (EC50=108 μM; Ki=113 μM) and mGluR4R (EC50=593 μM; Ki=112 μM)[1].

Molecular Weight

189.13

Formula

C₅H₇N₃O₅

CAS No.

52809-07-1

SMILES

O=C(O)[[email protected]@H](N)CN(C(N1)=O)OC1=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.
  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

Quisqualic acidL-Quisqualic acidiGluRmGluRIonotropic glutamate receptorsMetabotropic glutamate receptorsglutamatesubsetsexcitatoryaminoacidEAAAMPAInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

 

Salutation

Applicant Name *

 

Email address *

Phone number *

 

Organization name *

Department *

 

Requested quantity *

Country or Region *

     

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Quisqualic acid
Cat. No.:
HY-12597
Quantity:
MCE Japan Authorized Agent: