(RS)-AMPA hydrochloride
(RS)-AMPA hydrochloride ((±)-AMPA hydrochloride) is a glutamate analogue and a potent and selective excitatory neurotransmitter L-glutamic acid agonist. (RS)-AMPA hydrochloride hydrobromide does not interfere with binding sites for kainic acid or NMDA receptors.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 2922283-04-1
- 分子式: C7H11ClN2O4
- 分子量:222.63
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保管条件:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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生物活性
(RS)-AMPA hydrochloride induces dose-dependent depolarization in cultured fetal rat brainstem and lumbosacral spinal cord neurons by activating glutamate/quisqualate-preferring receptors[1].
(RS)-AMPA hydrochloride activates recombinant GluR-A/GluR-B AMPA receptors in cultured mammalian cells[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 2922283-04-1
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性状 Solid
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分子量 222.63
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分子式 C7H11ClN2O4
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Color White to off-white
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SMILES
O=C1NOC(C)=C1CC(C(O)=O)N.Cl
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別名
(±)-AMPA hydrochloride
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
溶剤 & 溶解度
DMSO : 125 mg/mL (561.47 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (275 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Hösli L, et al. Effects of the glutamate analogue AMPA and its interaction with antagonists on cultured rat spinal and brain stem neurones. Neurosci Lett. 1983;36(1):59-62. [Content Brief]
[2]. Sommer B, et al. Flip and flop: a cell-specific functional switch in glutamate-operated channels of the CNS. Science. 1990;249(4976):1580-1585. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.4918 mL | 22.4588 mL | 44.9176 mL | 112.2939 mL |
| 5 mM | 0.8984 mL | 4.4918 mL | 8.9835 mL | 22.4588 mL | |
| 10 mM | 0.4492 mL | 2.2459 mL | 4.4918 mL | 11.2294 mL | |
| 15 mM | 0.2995 mL | 1.4973 mL | 2.9945 mL | 7.4863 mL | |
| 20 mM | 0.2246 mL | 1.1229 mL | 2.2459 mL | 5.6147 mL | |
| 25 mM | 0.1797 mL | 0.8984 mL | 1.7967 mL | 4.4918 mL | |
| 30 mM | 0.1497 mL | 0.7486 mL | 1.4973 mL | 3.7431 mL | |
| 40 mM | 0.1123 mL | 0.5615 mL | 1.1229 mL | 2.8073 mL | |
| 50 mM | 0.0898 mL | 0.4492 mL | 0.8984 mL | 2.2459 mL | |
| 60 mM | 0.0749 mL | 0.3743 mL | 0.7486 mL | 1.8716 mL | |
| 80 mM | 0.0561 mL | 0.2807 mL | 0.5615 mL | 1.4037 mL | |
| 100 mM | 0.0449 mL | 0.2246 mL | 0.4492 mL | 1.1229 mL |
(RS)-AMPA hydrochloride 関連分類
HY-100815E 関連分類
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