2922283-04-1
Chemical Structure
(RS)-AMPA hydrochloride
Synonym(s): (±)-AMPA hydrochloride
- CAS No.: 2922283-04-1
- Formula:C7H11ClN2O4
- Molecular Weight:222.63
InChIKey: CKVBWVWGMKTZAG-UHFFFAOYSA-N
SMILES: O=C1NOC(C)=C1CC(C(O)=O)N.Cl
Biological Activity: (RS)-AMPA hydrochloride ((±)-AMPA hydrochloride) is a glutamate analogue and a potent and selective excitatory neurotransmitter L-glutamic acid agonist. (RS)-AMPA hydrochloride hydrobromide does not interfere with binding sites for kainic acid or NMDA receptors[1][2].
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(RS)-AMPA hydrochloride | (RS)-AMPA hydrochloride ((±)-AMPA hydrochloride) is a glutamate analogue and a potent and selective excitatory neurotransmitter L-glutamic acid agonist. (RS)-AMPA hydrochloride hydrobromide does not interfere with binding sites for kainic acid or NMDA receptors. | |||||||||||||||||||||
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- [1]. Hösli L, et al. Effects of the glutamate analogue AMPA and its interaction with antagonists on cultured rat spinal and brain stem neurones. Neurosci Lett. 1983;36(1):59-62. [Content Brief]
- [2]. Sommer B, et al. Flip and flop: a cell-specific functional switch in glutamate-operated channels of the CNS. Science. 1990;249(4976):1580-1585. [Content Brief]
Keywords