GPR65 Protein, Human (Cell-Free, His)
Based on 1 Customer Validation
GPR65 Protein, a receptor for psychosine (PSY) and related glycosphingolipids, is vital in immune responses. It preserves lysosome function, aiding phagocytosis for intracellular bacteria clearance. GPR65's involvement in activation-induced cell death or T-cell differentiation suggests its potential regulatory role in immune processes. GPR65 Protein, Human (Cell-Free, His) is the recombinant human-derived GPR65 protein, expressed by E. coli Cell-free , with N-10*His labeled tag.
- Species: Human
- Source: E. coli Cell-free
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Storage:Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
- Help & FAQs
Biological Activity
GPR65 Protein, a receptor for psychosine (PSY) and related glycosphingolipids, is vital in immune responses. It preserves lysosome function, aiding phagocytosis for intracellular bacteria clearance. GPR65's involvement in activation-induced cell death or T-cell differentiation suggests its potential regulatory role in immune processes. GPR65 Protein, Human (Cell-Free, His) is the recombinant human-derived GPR65 protein, expressed by E. coli Cell-free , with N-10*His labeled tag.
The GPR65 Protein functions as a receptor for the glycosphingolipid psychosine (PSY) and various related glycosphingolipids. It plays a crucial role in immune response by preserving lysosome function and facilitating phagocytosis-mediated clearance of intracellular bacteria. Additionally, GPR65 may be implicated in activation-induced cell death or T-cell differentiation, indicating its potential regulatory role in immune processes.
Technical Parameters
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Species Human
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Source E. coli Cell-free
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Tag N-10*His
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Accession
Q8IYL9 (M1-E337)
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Gene ID8477
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Molecular Construction
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N-term
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10*His
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GPR65 (M1-E337)
Accession # Q8IYL9 -
C-term
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Protein Length
Full Length
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Synonyms
GPR65; G-Protein Coupled Receptor 65; G Protein-Coupled Receptor 65; HTDAG8; TDAG8; Psychosine Receptor; T-Cell Death-Associated Gene 8 Protein
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AA Sequence
MNSTCIEEQHDLDHYLFPIVYIFVIIVSIPANIGSLCVSFLQAKKESELGIYLFSLSLSDLLYALTLPLWIDYTWNKDNWTFSPALCKGSAFLMYMNFYSSTAFLTCIAVDRYLAVVYPLKFFFLRTRRFALMVSLSIWILETIFNAVMLWEDETVVEYCDAEKSNFTLCYDKYPLEKWQINLNLFRTCTGYAIPLVTILICNRKVYQAVRHNKATENKEKKRIIKLLVSITVTFVLCFTPFHVMLLIRCILEHAVNFEDHSNSGKRTYTMYRITVALTSLNCVADPILYCFVTETGRYDMWNILKFCTGRCNTSQRQRKRILSVSTKDTMELEVLE
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Predicted Molecular Mass
40.8 kDa
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Purity
≥ 90%, as determined by reducing SDS-PAGE.
Product Properties
Lyophilized powder.
Lyophilized from a 0.22 μm filtered solution of 20 mM Tris-HCl, 0.15 M NaCl, 0.05% Brij-78, 6% trehalose, pH 8.0.
Note: For SPR assay, please replace the buffer. Primary amine components (e.g., Tris, imidazole) can affect protein-coupled chips.
<1 EU/μg, determined by LAL method.
It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O.
Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
Room temperature in continental US; may vary elsewhere.
Documentation
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Data Sheet (237 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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