1. Recombinant Proteins
  2. Receptor Proteins
  3. Cell Adhesion Molecules (CAMs)
  4. OMGP Protein, Mouse (HEK293, His)

OMGP Protein, Mouse (HEK293, His)

Cat. No.: HY-P76527
Handling Instructions

OMGP protein is a cell adhesion molecule that plays a crucial role in the interactive process necessary for myelination in the central nervous system. It accomplishes this by binding to RTN4R, facilitating the formation and maintenance of myelin sheaths. OMGP Protein, Mouse (HEK293, His) is the recombinant mouse-derived OMGP protein, expressed by HEK293 , with C-His labeled tag. The total length of OMGP Protein, Mouse (HEK293, His) is 221 a.a., with molecular weight of ~44 KDa.

For research use only. We do not sell to patients.

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Description

OMGP protein is a cell adhesion molecule that plays a crucial role in the interactive process necessary for myelination in the central nervous system. It accomplishes this by binding to RTN4R, facilitating the formation and maintenance of myelin sheaths. OMGP Protein, Mouse (HEK293, His) is the recombinant mouse-derived OMGP protein, expressed by HEK293 , with C-His labeled tag. The total length of OMGP Protein, Mouse (HEK293, His) is 221 a.a., with molecular weight of ~44 KDa.

Background

OMGP Protein, a membrane-associated protein, is involved in regulating axonal growth and neural development. It interacts with Nogo receptors, inhibiting axonal regeneration. OMGP Protein's role in neural plasticity makes it a potential target for therapeutic interventions aimed at promoting nerve regeneration and functional recovery in neurological disorders and injuries.

Species

Mouse

Source

HEK293

Tag

C-His

Accession

Q63912 (I25-T245)

Gene ID

18377  [NCBI]

Molecular Construction
N-term
OMGP (I25-T245)
Accession # Q63912
His
C-term
Synonyms
Oligodendrocyte-myelin glycoprotein; OMG
Molecular Weight

Approximately 44 kDa.

Purity

Greater than 95% as determined by reducing SDS-PAGE

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation

OMGP Protein, Mouse (HEK293, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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OMGP Protein, Mouse (HEK293, His)
Cat. No.:
HY-P76527
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