P2X3 Protein, Human (HEK293)
Based on 1 Customer Validation
P2X3 Protein, Human (HEK293) is the recombinant human-derived P2X3, expressed by HEK293 , with tag Free labeled tag. ,
- Species: Human
- Source: HEK293
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Storage:Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
- Help & FAQs
Biological Activity
P2X3 Protein, Human (HEK293) is the recombinant human-derived P2X3, expressed by HEK293 , with tag Free labeled tag. ,
P2X3 is an extracellular ATP-activated non-selective cation channel (PubMed:10440098, PubMed:27626375, PubMed:29674445, PubMed:31232692). It plays a particularly important role in sensory neurons, where its activation is critical for gustatory, nociceptive responses, visceral reflexes, and sensory hypersensitization (By similarity).
Technical Parameters
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Species Human
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Source HEK293
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Tag Tag Free
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Accession
P56373 (D6-E363, T13P, S15V, V16I)
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Gene ID5024
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Protein Length
Partial
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Synonyms
P2RX3; Purinergic Receptor P2X, Ligand Gated Ion Channel, 3; Purinergic Receptor P2X 3; Purinergic Receptor P2X3; P2X3; P2X Receptor, Subunit 3; P2X Purinoceptor 3; Purinergic Receptor; ATP Receptor; Purinoceptor P2X3; Purinergic Receptor P2X, Ligand-Gate
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AA Sequence
DFFTYETPKVIVVKSWTIGIINRVVQLLIISYFVGWVFLHEKAYQVRDTAIESSVVTKVKGSGLYANRVMDVSDYVTPPQGTSVFVIITKMIVTENQMQGFCPESEEKYRCVSDSQCGPERLPGGGILTGRCVNYSSVLRTCEIQGWCPTEVDTVETPIMMEAENFTIFIKNSIRFPLFNFEKGNLLPNLTARDMKTCRFHPDKDPFCPILRVGDVVKFAGQDFAKLARTGGVLGIKIGWVCDLDKAWDQCIPKYSFTRLDSVSEKSSVSPGYNFRFAKYYKMENGSEYRTLLKAFGIRFDVLVYGNAGKFNIIPTIISSVAAFTSVGVGTVLCDIILLNFLKGADQYKAKKFEEVNE
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Predicted Molecular Mass
40.4 kDa
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Purity
≥ 90%, as determined by reducing SDS-PAGE.
Product Properties
Solution.
Supplied as a 0.22 μm filtered solution of 20 mM HEPES pH 7.5, 150 mM NaCl, 0.03% (w/v) GDN, 0.5 mM TCEP.
<1 EU/μg, determined by LAL method.
Please use rapid thawing with running water to thaw the protein.
Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
Shipping with dry ice.
Documentation
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Data Sheet (236 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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