UB2L5 Protein, Human (sf9)

QDPR Protein, operating as a catalyst, converts quinonoid dihydrobiopterin into tetrahydrobiopterin, crucial for balancing biopterin cofactors in cellular metabolism. Tetrahydrobiopterin serves as an essential coenzyme in neurotransmitter synthesis and phenylalanine breakdown, emphasizing QDPR's regulatory role in diverse metabolic pathways. UB2L5 Protein, Human (sf9) is the recombinant human-derived UB2L5 protein, expressed by sf9 insect cells , with tag free.

For research use only. We do not sell to patients.
  • Species: Human
  • Source: Sf9 insect cells
  • Storage:
    Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
  • Biological Activity
  • Technical Parameters
  • Product Properties
  • Documentation
  • Help & FAQs

Biological Activity

Description

QDPR Protein, operating as a catalyst, converts quinonoid dihydrobiopterin into tetrahydrobiopterin, crucial for balancing biopterin cofactors in cellular metabolism. Tetrahydrobiopterin serves as an essential coenzyme in neurotransmitter synthesis and phenylalanine breakdown, emphasizing QDPR's regulatory role in diverse metabolic pathways. UB2L5 Protein, Human (sf9) is the recombinant human-derived UB2L5 protein, expressed by sf9 insect cells , with tag free.

Background

QDPR protein plays a pivotal role in cellular biopterin metabolism by catalyzing the conversion of quinonoid dihydrobiopterin into tetrahydrobiopterin. This enzymatic activity is crucial for maintaining the proper balance of biopterin cofactors, as tetrahydrobiopterin is an essential coenzyme involved in various enzymatic reactions, including neurotransmitter synthesis and the breakdown of phenylalanine. The catalytic function of QDPR highlights its significance in regulating biopterin levels and, consequently, its impact on diverse metabolic pathways within the cell.

Technical Parameters

  • Species Human
  • Source Sf9 insect cells
  • Tag Tag Free
  • Accession
  • Gene ID
  • Molecular Construction
    • N-term
    • UB2L5 (A2-D154)
      Accession # A0A1B0GUS4
    • C-term
  • Protein Length

    Full Length of Mature Protein

  • Synonyms

    UBE2L5; Ubiquitin Conjugating Enzyme E2 L5; UBE2L5P; Ubiquitin‑Conjugating Enzyme E2 L5; Ubiquitin‑Protein Ligase L5; Ubiquitin Conjugating Enzyme E2L 5 (Pseudogene); Ubiquitin Conjugating Enzyme E2 L5, Pseudogene; UBCH7N2

  • AA Sequence

    AASRRLMKELEEIRKCGMENFRNIQVDEANLLTWQGLIVPDNPPYNKGAFRIEINFPAEYPFKPPRITFKTKIYHPNIDEKGQVCLPVISAENWKPATKTDQVIQSLIALVNDPQPEHPLRADLAEEYSNDRKKFCKNAEEFTKKYGEKRPVD

  • Purity

    ≥ 90%, as determined by reducing SDS-PAGE.

Product Properties

Appearance

Solution.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Reconstitution

Please use rapid thawing with running water to thaw the protein.

Storage & Stability

Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping

Shipping with dry ice.

Calculators

Reconstitution Calculator

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) Volume (to add to vial)
=
Mass (in vial) Mass (in vial)
÷
Desired Reconstitution Concentration Desired Reconstitution Concentration
Dilution Calculator

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

Concentration (start) Concentration (start)
×
Volume (start) Volume (start)
=
Concentration (final) Concentration (final)
×
Volume (final) Volume (final)
The Specific Activity Calculator Equation
  • Specific Activity (Unit/mg)
  • Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) Specific Activity (Unit/mg)
Unit/mg
= 106 ÷
Biological Activity (ED50) Biological Activity (ED50)
106 ÷
ng/mL
MOQ
Minimum order quantity
100 mg

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