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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
14 Results for "
ECE1
" in MedChemExpress (MCE) Product Catalog:
Products (14)
14 Results for "ECE1" in MCE Product Catalog:
Cat. No.: HY-P3749
CAS No.: 323577-36-2
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Cat. No.: HY-B1237
CAS No.: 54767-75-8
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Suloctidil is an orally active calcium channel blocker and antifungal agent. Suloctidil antagonizes vasoconstriction induced by norepinephrine, angiotensin and serotonin. Suloctidil inhibits platelet function and exhibits neuroprotective effects. Suloctidil exerts inhibitory effects on Candida albicans biofilm and virulence. Suloctidil can be used in research on vasospasm relief, antithrombosis and superficial candidiasis [1] .
Cat. No.: HY-RS04133
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ECE1 Human Pre-designed siRNA Set A contains three designed siRNAs for ECE1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-178732
CAS No.: 1463913-43-0
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AB-22, a vinyl sulfate compound, is an orally active antifungal agent. AB-22 inhibits hyphal growth and biofilm initiation by inhibiting the gene expression of ALS3, HWP1, and ECE1 in Candida albicans SC5314 cells. AB-22 can be used for the research of infrction, such as systemic candidiasis [1].
Cat. No.: HY-RS18611
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Ece1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ece1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS25097
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Ece1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Ece1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-N11772
CAS No.: 875455-92-8
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Cat. No.: HY-107762
CAS No.: 261619-50-5
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CGS35066 is a potent and selective aminophosphonate inhibitor of endothelin-converting enzyme-1 (ECE-1). CGS 35066 inhibits the activity of human ECE-1 and rat kidney neutral endopeptidase 24.11 (NEP) in vitro with IC50 values of 22 nM and 2.3 μM, respectively [1].
Cat. No.: HY-119545
CAS No.: 179598-53-9
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PD159790 is a selective endothelin-converting enzyme-1 (ECE-1) inhibitor, with an EC50 of 28.1 μM [1] .
Cat. No.: HY-18211
CAS No.: 849066-09-7
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CGS 35601 is the inhibitor for endothelin-converting enzyme-1 (ECE-1), neutral endopeptidase 24.11 (NEP), and angiotensin-converting enzyme (ACE), with IC50s of 55, 2, and 22 nM, respectively. CGS 35601 suppresses the big endothelin-1 (big ET-1)- and angiotensin I-induced pressor response, and enhances circulation of atrial natriuretic peptide (ANP), regulates the cardiovascular function in SD rats [1].
Cat. No.: HY-184728
Antifungal agent-169 (compound 5p) is an antifungal agent that inhibits fluconazole (HY-B0101)-susceptible Candida albicans SC5314 with an MIC50 of 0.28 μM. Antifungal agent-169 reduces the expression levels of cAMP-PKA pathway-related genes including RAS1, EFG1, BCR1, ECE1 and HWP1 in Candida albicans. Antifungal agent-169 inhibits biofilm formation and hyphal growth of Candida albicans. Antifungal agent-169 can be used in studies related to Candida albicans infection [1].
Cat. No.: HY-N11772R
CAS No.: 875455-92-8
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
