261619-50-5
261619-50-5
Chemical Structure
CGS35066
- CAS No.: 261619-50-5
- Formula:C16H16NO6P
- Molecular Weight:349.28
IUPAC Name: (S)-3-(dibenzo[b,d]furan-3-yl)-2-((phosphonomethyl)amino)propanoic acid
InChIKey: CRUVAUSVWLATAE-ZDUSSCGKSA-N
SMILES: O=P(O)(O)CN[C@H](C(O)=O)CC1=CC=C(C2=CC=CC=C2O3)C3=C1
Biological Activity: CGS35066 is a potent and selective aminophosphonate inhibitor of endothelin-converting enzyme-1 (ECE-1). CGS 35066 inhibits the activity of human ECE-1 and rat kidney neutral endopeptidase 24.11 (NEP) in vitro with IC50 values of 22 nM and 2.3 μM, respectively[1].
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CGS35066 | CGS35066 is a potent and selective aminophosphonate inhibitor of endothelin-converting enzyme-1 (ECE-1). CGS 35066 inhibits the activity of human ECE-1 and rat kidney neutral endopeptidase 24.11 (NEP) in vitro with IC50 values of 22 nM and 2.3 μM, respectively. | |||||||||||||||||||||
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