323577-36-2
Chemical Structure
Mca-(ala7,lys(dnp)9)-bradykinin
- CAS No.: 323577-36-2
- Formula:C66H81N15O19
- Molecular Weight:1388.44
InChIKey: FDQLQIBWKJMUSI-HGGPOPJMSA-N
SMILES: O=C(N1[C@@H](CCC1)C(N2[C@@H](CCC2)C(NCC(N[C@H](C(N[C@@H](CO)C(N[C@@H](C)C(N[C@H](C(N[C@H](C(O)=O)CCCCNC3=C(C=C(C=C3)[N+]([O-])=O)[N+]([O-])=O)=O)CC4=CC=CC=C4)=O)=O)=O)CC5=CC=CC=C5)=O)=O)=O)[C@H](CCCNC(N)=N)NC(CC(C6=CC=C(OC)C=C6O7)=CC7=O)=O
Biological Activity: Mca-(ala7,lys(dnp)9)-bradykinin is a sensitive fluorogenic substrate for ECE-1 (endothelin-converting enzyme-1). The incorporation of a (7-methoxycoumarin-4-yl)acetyl (Mca) fluorescent group and a 2,4-dinitrophenyl (Dnp) quenching group has resulted in a large fluorescence increase upon substrate cleavage[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Mca-(ala7,lys(dnp)9)-bradykinin | 99.93% | Mca-(ala7,lys(dnp)9)-bradykinin is a sensitive fluorogenic substrate for ECE-1 (endothelin-converting enzyme-1). The incorporation of a (7-methoxycoumarin-4-yl)acetyl (Mca) fluorescent group and a 2,4-dinitrophenyl (Dnp) quenching group has resulted in a large fluorescence increase upon substrate cleavage. | ||||||||||||||||||||
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Keywords
