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Results for "

11-cis-Retinol

" in MedChemExpress (MCE) Product Catalog:

3

Inhibitors & Agonists

1

Natural
Products

Cat. No. 상품명 Target 연구분야 Chemical Structure
  • HY-116711
    11-cis-Retinal

    11-cis Retinaldehyde; 11-cis Vitamin A aldehyde

    		 Drug Derivative Endogenous Metabolite Neurological Disease
    11-cis-Retinal (11-cis Retinaldehyde; 11-cis Vitamin A aldehyde), oxidized form of 11-cis-Retinol (HY-W587807), is a naturally occurring visual component. 11-cis-Retinal binds to opsin in the mammalian visual system as an inverse agonist forming the inactive conformation of rhodopsin. 11-cis-Retinal plays a crucial role in vision, growth and development. 11-cis-Retinal can restore visual function in moths with visual impairments. 11-cis-Retinal can restore retinal function in an early-age LCA2 retinal degeneration 12 mouse model .
    11-cis-Retinal
  • HY-W587807
    11-cis-Retinol

    		Endogenous Metabolite Neurological Disease
    11-cis-Retinol, a form of retinol, can bind to RDH5. 11-cis-Retinol promote dark adaptation and recovery of photoresponsiveness of red cones but not of red rods .
    11-cis-Retinol
  • HY-E71179
    11-cis-Retinol dehydrogenase

    		Biochemical Assay Reagents Others
    11-cis-Retinol dehydrogenase (EC 1.1.1.315) catalyses the reduction of 11-cis-Retinol to 11-cis-retinal while the substrate is bound to the retinal-binding protein. This is a crucial step in the regeneration of 11-cis-retinal, the chromophore of rhodopsin. The enzyme can also accept other cis forms of retinol.
    11-cis-Retinol dehydrogenase

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