2 Results for "

1431368-48-7

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "1431368-48-7" in MCE Product Catalog:

Cat. No.: HY-100546
CAS No.: 1431368-48-7
Target:  

Histone Demethylase

Research Areas:  

Infection Metabolic Disease Cancer

GSK-LSD1, a chemical probe, is a LSD1 inhibitor. GSK-LSD1 reduces food intake and body weight, and improves insulin sensitivity and glycemic control in mouse models of obesity. GSK-LSD1 also ameliorates NAFLD. GSK-LSD1 inhibits SARS-CoV-2-triggered cytokine release in COVID-19 PBMCs. GSK-LSD1 also inhibits cancer growth and metastasis .
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14
14 Cited Publications
Cat. No.: HY-100546A
CAS No.: 2102933-95-7
Purity:  ≥98.0%
Research Areas:  

Cancer

GSK-LSD1 dihydrochloride is a potent, selective and irreversible lysine specific demethylase 1 (LSD1) inhibitor with an IC50 of 16 nM.
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