1 Result for "

2036081-86-2

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "2036081-86-2" in MCE Product Catalog:

Cat. No.: HY-118424
CAS No.: 2036081-86-2
Target:  

iGluR

JNJ-55511118 is a selective TARP γ-8 binding AMPA receptor modulator with oral bioavailability and blood-brain barrier permeability, with a Ki of 26 nM. JNJ-55511118 reduces voluntary intake of sweetened alcohol in male mice. In rodent models, JNJ-55511118 inhibits hippocampal neurotransmission, reduces specific electroencephalogram frequency bands, induces transient hyperlocomotion, impairs learning and memory abilities, and exerts anticonvulsant effects. JNJ-55511118 is applicable to research related to alcohol use disorder and seizures .
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