1 Result for "

2108714-20-9

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "2108714-20-9" in MCE Product Catalog:

Cat. No.: HY-146066
CAS No.: 2108714-20-9
Purity:  99.54%
α7 nAchR-JAK2-STAT3 agonist 1 is a potent α7 nAchR-JAK2-STAT3 agonist, with an IC50 value of 0.32 μM for nitric oxide (NO). α7 nAchR-JAK2-STAT3 agonist 1 effectively suppresses the expression of iNOS, IL-1β, and IL-6 in murine RAW264.7 macrophages. α7 nAchR-JAK2-STAT3 agonist 1 can inhibit LPS-induced NO release, NF-κB activation and cytokine production. α7 nAchR-JAK2-STAT3 can be used for researching sepsis .
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