1 Result for "

212844-54-7

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "212844-54-7" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-18299
CAS No.: 212844-54-7
Synonyms: NG 95
Target:  

CDK Parasite

Research Areas:  

Infection Cancer

Purvalanol B (NG 95) is a potent, selective, reversible and ATP-competitive inhibitor CDK, with IC50s of 6 nM, 6 nM, 9 nM, 6 nM for cdc2-cyclin B, CDK2-cyclin A, CDK2-cyclin E and CDK5-p35, respectively. Purvalanol B shows selectivity for CDK over a range of other protein kinases (IC50>1000 nM). Purvalanol B inhibits the growth a chloroquine-resistant strain of P. falciparum .
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