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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
1 Result for "
2149-70-4
" in MedChemExpress (MCE) Product Catalog:
Products (1)
1 Results for "2149-70-4" in MCE Product Catalog:
Synonyms: Nω-nitro-L-arginine; L-NOARG; L-NG-Nitroarginine
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NG-nitro-L-arginine (Nω-nitro-L-arginine; L-NOARG; L-NG-Nitroarginine) is a nitric oxide synthase (NO Synthase) inhibitor, with a Kd of 15 nM for constitutive NOS from bovine brain and a Ki of 4.4 μM for inducible NOS from mouse macrophages. NG-nitro-L-arginine competitively blocks the synthesis of NO from L-arginine; in addition, it inhibits endothelium-dependent vasodilation, and exhibits effects such as blood pressure elevation, heart rate reduction and vasoconstriction. NG-nitro-L-arginine regulates mitochondrial respiratory efficiency, antioxidant enzyme activity, lipid peroxidation level and tissue lead content in rats. NG-nitro-L-arginine can be used in studies related to cardiovascular diseases .
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
