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217817-01-1

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1 Results for "217817-01-1" in MCE Product Catalog:

Cat. No.: HY-130422
CAS No.: 217817-01-1
Synonyms: Tos-PEG4-Boc
Target:  

PROTAC Linkers

Research Areas:  

Cancer

Tos-PEG4-t-butyl ester (Tos-PEG4-Boc) is a PROTAC linker, which refers to the PEG composition. Tos-PEG4-t-butyl ester (Tos-PEG4-Boc) can be used in the synthesis of a series of PROTACs, such as BI-3663 (HY-111546). BI-3663 is a highly selective PTK2/FAK PROTAC, with cereblon ligands to hijack E3 ligases for PTK2 degradation, and inhibits PTK2 with an IC50 of 18 nM .
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