1 Result for "

2456294-92-9

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "2456294-92-9" in MCE Product Catalog:

Cat. No.: HY-150579
CAS No.: 2456294-92-9
Purity:  96.77%
Target:  

Keap1-Nrf2

Research Areas:  

Inflammation/Immunology Cancer

Keap1-Nrf2-IN-13 is a Keap1-Nrf2 protein–protein interaction (PPI) inhibitor with an IC50 value of 0.15 μM. Keap1-Nrf2-IN-13 has strong binding affinities to the Keap1 protein by forming hydrogen bond with the key polar residues (Asn414, Arg415, Arg483, Gln530). Keap1-Nrf2-IN-13 can be used in the research of oxidative stress-related and inflammatory diseases, including pulmonary fibrosis, chronic obstructive pulmonary disorder (COPD) and cancers .
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