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2649899-08-9

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "2649899-08-9" in MCE Product Catalog:

Cat. No.: HY-180057
CAS No.: 2649899-08-9
Target:  

Integrin

Research Areas:  

Inflammation/Immunology

α5β1 integrin-IN-1 is a potent and selective α5β1 integrin inhibitor with an IC50 value of approximately 0.4 nM (pIC50 = 9.4 M). α5β1 integrin-IN-1 disrupts the interaction between α5β1 integrin and fibronectin, thereby blocking smooth muscle tension transmission and α5β1 integrin-mediated cell adhesion. α5β1 integrin-IN-1 can be used in the research of asthma and allergic asthma.
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