1 Result for "

301312-49-2

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "301312-49-2" in MCE Product Catalog:

Cat. No.: HY-201256
CAS No.: 301312-49-2
Target:  

Bacterial MDM-2/p53

Research Areas:  

Infection

UCI-14 is a gltA1/lprQ modulator with in vitro anti-tuberculosis activity against drug-sensitive and multidrug-resistant mycobacteria. UCI-14 upregulates the expression of genes encoding citrate synthase I, downregulates the expression of genes encoding conserved mycobacterial lipoprotein, and alters the carbon metabolism of mycobacteria. UCI-14 reactivates the expression of wild-type p53 target genes in p53-mutated cells. UCI-14 can be used in the research of tuberculosis and cancer .
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