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3104460-09-2

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1 Results for "3104460-09-2" in MCE Product Catalog:

Cat. No.: HY-168088
CAS No.: 3104460-09-2
Research Areas:  

Cancer

DNMT1/HDAC-IN-1 (compound (R)-23a) is a DNMT1/HDAC dual inhibitor (HDAC1:IC50=0.05 μM), HDAC1 is a major HDAC isoform that interacts with DNMT1 in multiple protein complexes for transcriptional silencing of TSGs. DNMT1/HDAC-IN-1 can reshape the tumor immune microenvironment and induce tumor regression, and effectively reverse cancer-specific epigenetic abnormalities .
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