2 Results for "

330981-72-1

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "330981-72-1" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-107535
CAS No.: 330981-72-1
Purity:  99.84%
Target:  

GPR119 TRP Channel

Research Areas:  

Metabolic Disease

AS1269574 is a potent, orally available GPR119 agonist, with an EC50 of 2.5 μM in HEK293 cells expressing human GPR119. AS1269574 activates TRPA1 cation channels to stimulate glucagon-like peptide-1 (GLP-1) secretion. AS1269574 specifically induces glucose-dependent insulin secretion from pancreatic β-cells only under high-glucose conditions. AS1269574 has the potential for the research of type 2 diabetes .
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Cat. No.: HY-107535R
CAS No.: 330981-72-1
Research Areas:  

Metabolic Disease

AS1269574 (Standard) is the analytical standard of AS1269574 (HY-107535). This product is intended for research and analytical applications. AS1269574 is a potent, orally available GPR119 agonist, with an EC50 of 2.5 μM in HEK293 cells expressing human GPR119. AS1269574 activates TRPA1 cation channels to stimulate glucagon-like peptide-1 (GLP-1) secretion. AS1269574 specifically induces glucose-dependent insulin secretion from pancreatic β-cells only under high-glucose conditions. AS1269574 has the potential for the research of type 2 diabetes .
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