1 Result for "

4-Methoxylonchocarpin

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "4-Methoxylonchocarpin" in MCE Product Catalog:

4-Methoxylonchocarpin
4-Methoxylonchocarpin
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Cat. No.: HY-N11768
CAS No.: 51589-67-4
Category:  

Monophenols Phenols Plants Moraceae Dorstenia mannii Hook.f.

Target:  

NF-κB Interleukin Related Toll-like Receptor (TLR)

4-Methoxylonchocarpin is an orally active anti-inflammatory agent. 4-methoxylonchocarpin inhibits the binding of LPS to Toll-like Receptor (TLR) TLR4 to inhibit NF-κB activation and TNF Receptor and IL-6 expression. 4-Methoxylonchocarpin also inhibits the phosphorylation of TGF-beta activated kinase 1 and TNBS-induced expression of IL-1β, IL-17A, and TNF. 4-methoxylonchocarpin can improve 2,4, 6-trinitrobenzene sulfonic acid (TNBS)-induced colitis mouse model .
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