2 Results for "

4049-38-1

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "4049-38-1" in MCE Product Catalog:

(±)-Eriodictyol
(±)-Eriodictyol
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Cat. No.: HY-N0637A
CAS No.: 4049-38-1
Synonyms: (±)-Huazhongilexone; Dihydroluteolin
Category:  

Lythraceae Lawsonia inermis L. Flavonoids Flavones Plants

Target:  

Melanocortin Receptor TRP Channel

(±)-Eriodictyol ((±)-Huazhongilexone; Dihydroluteolin) is an orally active TRPV1 receptor antagonist (IC50=44-47 nM, rTRPV1) with antioxidant and anti-inflammatory activities. (±)-Eriodictyol effectively inhibits lipid peroxidation and the release of proinflammatory cytokines by specifically antagonizing the TRPV1 receptor and activating the Nrf2 signaling pathway. (±)-Eriodictyol reduces the levels of ICAM-1, VEGF, eNOS and TNF-α in the retina and maintains the integrity of the blood-retinal barrier. (±)-Eriodictyol alleviates oxidative stress-induced apoptosis and hyperalgesia, enhances the activity and cytotoxicity of immune cells (such as B lymphocytes, NK cells and macrophages), and increases the levels of antioxidant enzymes simultaneously. (±)-Eriodictyol can be used in the research of diabetic retinopathy, acute lung injury and various pain-related diseases .
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(±)-Eriodictyol (Standard)
(±)-Eriodictyol (Standard)
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Cat. No.: HY-N0637AR
CAS No.: 4049-38-1
Synonyms: (±)-Huazhongilexone (Standard); Dihydroluteolin (Standard)
Category:  

Lythraceae Lawsonia inermis L. Flavonoids Flavones Plants

Target:  

Reference Standards Melanocortin Receptor TRP Channel

3-Chlorobenzoic acid (Standard) is the analytical standard of 3-Chlorobenzoic acid. This product is intended for research and analytical applications. (±)-Eriodictyol ((±)-Huazhongilexone; Dihydroluteolin) is an orally active TRPV1 receptor antagonist (IC50=44-47 nM, rTRPV1) with antioxidant and anti-inflammatory activities. (±)-Eriodictyol effectively inhibits lipid peroxidation and the release of proinflammatory cytokines by specifically antagonizing the TRPV1 receptor and activating the Nrf2 signaling pathway. (±)-Eriodictyol reduces the levels of ICAM-1, VEGF, eNOS and TNF-α in the retina and maintains the integrity of the blood-retinal barrier. (±)-Eriodictyol alleviates oxidative stress-induced apoptosis and hyperalgesia, enhances the activity and cytotoxicity of immune cells (such as B lymphocytes, NK cells and macrophages), and increases the levels of antioxidant enzymes simultaneously. (±)-Eriodictyol can be used in the research of diabetic retinopathy, acute lung injury and various pain-related diseases .
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