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515-49-1

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Cat. No.: HY-100010
CAS No.: 515-49-1
Target:  

Fungal Antifolate

Research Areas:  

Infection

Sulfathiourea is an inhibitor of Pneumocystis carinii dihydropteroate synthetase (dihydropteroate synthetase), with an IC50 of 0.022 μM and a Ki of 16.5 nM. Sulfathiourea blocks folate biosynthesis by inhibiting the enzyme that links 7,8-dihydro-6-hydroxymethylpterin pyrophosphate with p-aminobenzoic acid to form dihydropteroate. Sulfathiourea can be used in research related to *Pneumocystis carinii* pneumonia .
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