2. Anti-infection Cell Cycle/DNA Damage
  3. Fungal Antifolate
  4. Sulfathiourea

Sulfathiourea is an inhibitor of Pneumocystis carinii dihydropteroate synthetase (dihydropteroate synthetase), with an IC50 of 0.022 μM and a Ki of 16.5 nM. Sulfathiourea blocks folate biosynthesis by inhibiting the enzyme that links 7,8-dihydro-6-hydroxymethylpterin pyrophosphate with p-aminobenzoic acid to form dihydropteroate. Sulfathiourea can be used in research related to *Pneumocystis carinii* pneumonia.

For research use only. We do not sell to patients.

Sulfathiourea

Sulfathiourea Chemical Structure

CAS No. : 515-49-1

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Sulfathiourea Related Antibodies

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Description

Sulfathiourea is an inhibitor of Pneumocystis carinii dihydropteroate synthetase (dihydropteroate synthetase), with an IC50 of 0.022 μM and a Ki of 16.5 nM. Sulfathiourea blocks folate biosynthesis by inhibiting the enzyme that links 7,8-dihydro-6-hydroxymethylpterin pyrophosphate with p-aminobenzoic acid to form dihydropteroate. Sulfathiourea can be used in research related to *Pneumocystis carinii* pneumonia[1].

In Vitro

Sulfathiourea potently inhibits recombinant *Pneumocystis carinii* dihydropteroate synthase, with an IC50 of 22 nM and a Ki of 16.5 nM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Sulfathiourea Related Antibodies
Molecular Weight

231.29

Formula

C7H9N3O2S2
CAS No.
SMILES

O=S(=O)(NC(=S)N)C1=CC=C(N)C=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Sulfathiourea Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Sulfathiourea515-49-1FungalAntifolatePneumocystis carinii7,8-dihydro-6-hydroxymethylpterin pyrophosphatedihydropteroate synthetasedihydropteroatefolate biosynthesispneumocystis carinii pneumoniap-aminobenzoic acidInhibitorinhibitorinhibit

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