1 Result for "

53861-57-7

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "53861-57-7" in MCE Product Catalog:

Cat. No.: HY-131642
CAS No.: 53861-57-7
Synonyms: H-Gla-OH
Target:  

mGluR

Research Areas:  

Neurological Disease

L-γ-Carboxyglutamic acid (H-Gla-OH) is a mGluR2 antagonist with an IC50 of 102 μM. L-γ-Carboxyglutamic acid binds to the mGluR2 receptor site via the overlapping extended amino acid conformation of its amino and carboxyl groups with glutamic acid, and its additional acidic group locates in a restricted region, thereby blocking the full activation of the receptor. L-γ-Carboxyglutamic acid can be used for the research of neurological disorders .
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