1 Result for "

670267-73-9

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "670267-73-9" in MCE Product Catalog:

Cat. No.: HY-155727
CAS No.: 670267-73-9
Target:  

Sirtuin Apoptosis

Research Areas:  

Cancer

Sirt1/2-IN-2 (compound hsa55) is a dual inhibitor of SIRT1/2 with IC50s of 1.8 μM (SIRT1) and 2.4 μM (SIRT2), respsectivley. Sirt1/2-IN-2 completely blocks p53 deacetylation, and increase of p53 and α-tubulin acetylation. Sirt1/2-IN-2 induces apoptosis and shows anti-proliferation activity against human leukemia cell lines .
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