1 Result for "

69809-46-7

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "69809-46-7" in MCE Product Catalog:

(2E,6E,10E)-12-Hydroxyfarnesol
(2E,6E,10E)-12-Hydroxyfarnesol
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Cat. No.: HY-N20617
CAS No.: 69809-46-7
Category:  

Natural Products Leguminosae Plants Astragalus lentiginosus Douglas ex Hook.

Target:  

Drug Metabolite Endogenous Metabolite Cytochrome P450

(2E,6E,10E)-12-Hydroxyfarnesol is a metabolite of Farnesol (HY-Y0248A). (2E,6E,10E)-12-Hydroxyfarnesol forms via CYP2E1- and CYP2C19-mediated ω-hydroxylation of Farnesol in mammalian systems, and via CYP2E1-catalyzed selective hydroxylation of Farnesol in mammalian cells. (2E,6E,10E)-12-Hydroxyfarnesol is produced by the endophytic fungus Aspergillus sp. AST0006. When cholesterol synthesis is blocked, (2E,6E,10E)-12-Hydroxyfarnesol acts as a precursor for the formation of α,β-dicarboxylic acid .
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