1 Result for "

851600-86-7

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "851600-86-7" in MCE Product Catalog:

Cat. No.: HY-50882
CAS No.: 851600-86-7
Target:  

γ-secretase

Research Areas:  

Neurological Disease

ELN318463 is an amyloid precursor protein (APP) selective γ-secretase inhibitor. ELN318463 shows differential inhibition of presenilin (PS1)- and PS2-comprised γ-secretase with EC50s of 12 nM and 656 nM for PS1 and PS2, respectively. ELN318463 is 51-fold more selective for PS1 .
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