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865784-65-2

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "865784-65-2" in MCE Product Catalog:

Cat. No.: HY-146432
CAS No.: 865784-65-2
Research Areas:  

Cancer

Antitumor agent-60 (compound 20) is a potent antitumor agent, targeting RAS-RAF signaling pathway and binding to CRAF with a Kd value of 3.93 μM. Antitumor agent-60 induces apoptosis by blocking cell cycle at G2/M phase. Antitumor agent-60 enhances the level of p53 and ROS. Antitumor agent-60 causes oval and irregular nucleus in cancer cells. Antitumor agent-60 can suppress the growth of tumor to some extent in A549 xenograft model .
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